Spirit of 1848

C2lc20677c 1841..1848

Biomolecules inside a microfluidic system can be used to solve computational problems, such as theorem proving, which is an important class of logical reasoning problems. In this article, the Boolean variables (literals) were represented using single-stranded DNA molecules, and theorem proving was performed by the hybridization and ligation of these variables into a double-stranded ‘‘solution’’...

Ddh197 1839..1848

Human SCO1 and SCO2 are paralogous genes that code for metallochaperone proteins with essential, but poorly understood, roles in copper delivery to cytochrome c oxidase (COX). Mutations in these genes produce tissue-specific COX deficiencies associated with distinct clinical phenotypes, although both are ubiquitously expressed. To investigate the molecular function of the SCO proteins, we chara...

Dev104018 1848..1856

In the adultDrosophilamidgut the bonemorphogenetic protein (BMP) signaling pathway is required to specify and maintain the acidsecreting region of the midgut known as the copper cell region (CCR). BMP signaling is also involved in themodulation of intestinal stem cell (ISC) proliferation in response to injury. How ISCs are able to respond to the same signaling pathway in a regionally different ...

Recollecting the Spirit of Jihad

The Spirit of Teaching